In addition to the villains, a group of medics used the Old Gotham Cathedral as a medical center. Finally, Hush kept a hideout in Park Row, and used it to surgically remove his victims' faces construct for the purpose of constructing a new face for himself. The Mad Hatter likewise maintained a hidden lair in Park Row, while he secretly built his own gang of mind-controlled minions.

Catwoman had an apartment in one of the buildings on the northeastern part of the district. Several other notable denizens of Arkham City used Park Row as their bases of operations. Prior to Two-Face moving in, Calendar Man had lived in the Courthouse and was locked in one of the cells by Two-Face's Gang. When Gotham's criminals were thrown into Arkham City, Two-Face and his gang claimed Park Row as their home turf, and used the Solomon Wayne Courthouse as their headquarters. Park Row was one of the districts of Gotham City that became part of Arkham City. Crime Alley also appeared in the second of the hallucinations that Batman suffered due to Scarecrow's Fear Toxin, where he relived his parent's murder. Batman's final confrontation with Black Mask took place at the Old Gotham Cathedral.Д¬rime Alley could be accessible by a Combat Challenge Map. Anarky, another one of Batman's adversaries, as well as his followers, holed up inside the Solomon Wayne Courthouse.

From there, he conducted research into refining TN-1 and into determining the identity of Batman.

Bane maintained a hidden, underground base on the edge of Park Row.

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